Author

João Sobral

Instituto Gulbenkian de CiênciaORCID 0000-0002-7161-0661Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1

Frequent Co-Authors

Miguel AntunesiD· 2 shared Natalia Suárez VargasiD· 2 shared Sebastião van UdeniD· 2 shared Abdul MateeniD· 1 shared Anna Kolková· 1 shared Carolina SilvaiD· 1 shared Claudio MedanaiD· 1 shared Daniela PachecoiD· 1 shared

Activity by Year

2018-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersMicrobiology

Miguel AntunesORCID

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3 papers

Recent·Most cited

MicrobiologyGut MicrobiologyPeer-reviewedOct 23, 2025

Gut3Gel: A High Throughput Mucus Model for Culturing Human Intestinal Microbiota

Natalia Suárez Vargas, Miguel Antunes, João Sobral…·Daniela Peneda Pacheco

Gut3Gel is a new in vitro mucus model that supports diverse intestinal microbiota growth and metabolic activity, offering a scalable platform for microbiota research.

2 citations

humanbulk RNA-seq

MicrobiologybioRxivPreprintMay 29, 2025

Gut3Gel as an in vitro model to investigate dietary modulation of the intestinal microbiota: An inulin supplementation case study

Miguel Antunes, Lucy Jongen, Abdul Mateen…·Daniela Pacheco

The paper evaluates Gut3Gel as a model to study inulin's effects on the gut microbiota, finding it captures inter-individual responses and prebiotic effects.

DOI 10.1101/2025.05.29.656766

humanbulk RNA-seq

Developmental BiologyEMBO ReportsPeer-reviewedJul 23, 2018

The Trithorax group protein dMLL3/4 instructs the assembly of the zygotic genome at fertilization

Pedro Prudêncio, Leonardo Gastón Guilgur, João Sobral…·Paulo Navarro‐Costa

This study shows that dMLL3/4 is essential for the transition to embryo fate at fertilization by promoting gene expression needed for zygotic genome assembly.

11 citations

Drosophilastatistical model