Author

Leonardo Gastón Guilgur

Instituto Gulbenkian de CiênciaORCID 0000-0002-8197-5920Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:Drosophila· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Organism:multiple species· 1

Frequent Co-Authors

Jörg Dieter BeckeriD· 2 shared Paulo Navarro‐CostaiD· 2 shared Pedro PrudêncioiD· 2 shared Alexandra TavaresiD· 1 shared Ana NóvoaiD· 1 shared Ana S Leocádio· 1 shared Chandra Shekhar MisraiD· 1 shared Daniel SobraliD· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersDevelopmental Biology

Jörg Dieter BeckerORCID

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3 papers

Recent·Most cited

Developmental BiologybioRxivPreprintMar 2, 2022

The conserved genetic program of male germ cells uncovers ancient regulators of human spermatogenesis

Rion Brattig Correia, Joana M. Almeida, Margot Julia Wyrwoll…·Paulo Navarro‐Costa

The paper identifies a conserved genetic program in male germ cells across species, revealing 161 new spermatogenesis genes and three potential causes of human infertility.

20 citations

multiple speciesbulk RNA-seq

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Developmental BiologyPLoS BiologyPeer-reviewedFeb 22, 2019

Delayed aneuploidy stress response of neural stem cells impairs adult lifespan in flies

Mihailo Mirkovic, Leonardo Gastón Guilgur, Alexandra Tavares…·Raquel A. Oliveira

The paper shows that delayed aneuploidy stress response in neural stem cells during Drosophila development leads to motor defects and reduced lifespan.

21 citations

Drosophilaexperimental assay

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Developmental BiologyEMBO ReportsPeer-reviewedJul 23, 2018

The Trithorax group protein dMLL3/4 instructs the assembly of the zygotic genome at fertilization

Pedro Prudêncio, Leonardo Gastón Guilgur, João Sobral…·Paulo Navarro‐Costa

This study shows that dMLL3/4 is essential for the transition to embryo fate at fertilization by promoting gene expression needed for zygotic genome assembly.

11 citations

Drosophilastatistical model

𝕏 PostBluesky