Author

Justina Pajarskienė

State Research Institute Centre for Innovative MedicineORCID 0000-0002-7166-0036Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Aida KaušylėiD· 2 shared Alexei VerkhratskyiD· 2 shared Augustas PivoriūnasiD· 2 shared Karolina KriaučiūnaitėiD· 2 shared Agnė PociūtėiD· 1 shared Dmitry LimiD· 1 shared Virginijus TunaitisiD· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 19 mutual co-author links

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2 shared papersMolecular Biology

Aida KaušylėORCID

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2 papers

Recent·Most cited

Concentration-dependent duality of bFGF in regulation of barrier properties of human brain endothelial cells

Karolina Kriaučiūnaitė, Agnė Pociūtė, Aida Kaušylė, Justina Pajarskienė, Alexei Verkhratsky, Augustas Pivoriūnas

This study shows that autocrine bFGF is essential for BCEC barrier function, while exogenous bFGF inhibits barrier resistance in a concentration-dependent manner.

Journal of Cellular Physiology · May 7, 2021Peer-reviewedMolecular Biology

Immortalised hippocampal astrocytes from 3xTG-AD mice fail to support BBB integrity in vitro: Role of extracellular vesicles in glial-endothelial communication

Karolina Kriaučiūnaitė, Aida Kaušylė, Justina Pajarskienė, Virginijus Tunaitis, Dmitry Lim, Alexei Verkhratsky, Augustas Pivoriūnas

This study shows that astrocytes from 3xTG-AD mice impair BBB integrity in vitro through paracrine mechanisms, as evidenced by reduced tight junction protein expression and TEER.

Cellular and Molecular Neurobiology · May 21, 2020Peer-reviewedNeuroscience