Loss of Activity-Induced Mitochondrial ATP Production Underlies the Synaptic Defects in a Drosophila model of ALS
Nicholas E. Karagas, Richa Gupta, Elham Rastegari, Kai Li Tan, Ho Hang Leung, Hugo Jozef Bellen, Kartik Venkatachalam, Ching‐On Wong
This paper identifies bioenergetic dysfunction due to reduced activity-induced mitochondrial ATP production as the cause of synaptic defects in a Drosophila ALS model.
Journal of Neuroscience · Sep 8, 2022Peer-reviewedNeuroscience