Tissues Guide Dependence of Treg on the Transferrin Receptor
Michelle Montoya, Yasmine T. Toudji, Ata Ur Rehman, A. Zhelonkin, KayLee K. Steiner, Teresa Tamborra-Walton, Katherine Nicole Gibson-Corley, Samantha C. St. Jean, Denis A. Mogilenko, Jeffrey C. Rathmell, Kelsey Voss
This study shows that loss of the transferrin receptor (CD71) in Treg cells leads to tissue-specific inflammation and autoimmunity, highlighting the role of CD71-iron metabolism in Treg stability and function.
bioRxiv · Feb 3, 2026 · PreprintImmunology