Cell BiologyBiochemical and Biophysical Research CommunicationsPeer-reviewed
In differentiated HL-60 neutrophil-like cells, MRP1- (ABCC1-) mediated glutathione efflux stimulated by BzATP and P2X7 receptor signalling regulates exosome release through nSMase activity
Erica Muriana Tintor, Anfal Sharif, Lúcia Moreno-Sάnchez…·Jameel M. Inal
This study identifies a pathway in neutrophil-like cells where P2X7 receptor activation via BzATP triggers redox changes and nSMase activity, promoting exosome release.
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