Amin Ardeshirdavani

WiNGS enables federated analysis of omics data across a consortium without centralized storage, supporting variant interpretation for rare disease diagnosis.

This study evaluates five NIPT aneuploidy detection tools using clinically validated samples, finding that lower sequencing coverage increases false-negative and false-positive rates.

The paper analyzes genetic variation in ACE2 across Iranian populations to assess its association with COVID-19 severity, finding limited impact of exonic variants on disease outcomes.