The role of Tyr34 in proton-coupled electron transfer of human manganese superoxide dismutase
Jahaun Azadmanesh, Katelyn Slobodnik, Lucas R. Struble, Jeffrey J. Lovelace, Erika A. Cone, Medhanjali Dasgupta, William E. Lutz, Siddhartha Kumar, Amarnath Natarajan, Leighton Coates, Kevin L. Weiss, Dean A. A. Myles, Thomas Kröll, Gloria E. O. Borgstahl
This study investigates the role of Tyr34 in MnSOD catalysis using neutron diffraction, X-ray spectroscopy, and quantum chemistry calculations, revealing its impact on proton-coupled electron transfer.
Nature Communications · Feb 22, 2025Peer-reviewedBiochemistry