Leighton Coates

This study uses neutron crystallography and simulations to analyze proton sharing in low-barrier hydrogen bonds in DJ-1 and YajL, showing how mutations affect proton delocalization and mobility.

The paper reports high-resolution 13C and 15N backbone chemical shift assignments for Toho-1 β-lactamase using advanced solid-state NMR techniques, confirming conserved secondary structure.

This study investigates the role of Tyr34 in MnSOD catalysis using neutron diffraction, X-ray spectroscopy, and quantum chemistry calculations, revealing its impact on proton-coupled electron transfer.

The paper investigates the mechanism of product inhibition in human MnSOD by combining neutron diffraction and X-ray absorption spectroscopy to determine the atomic and electronic structures of the enzyme in different states.