Author

William Dowhan

The University of Texas Health Science Center at HoustonORCID 0000-0002-7252-3607Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell signaling & trafficking· 1 Assay:cryo-EM· 1 Approach:deep learning· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1 Organism:yeast· 1

Frequent Co-Authors

Abhishek SingharoyiD· 1 shared Alberto PéreziD· 1 shared Chitrak GuptaiD· 1 shared Chun Kit ChaniD· 1 shared Corey F. HryciD· 1 shared Eugenia MileykovskayaiD· 1 shared Jonathan T. NguyeniD· 1 shared Kevin ReddingiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiophysics

Abhishek SingharoyORCID

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1 paper

Recent·Most cited

Transient protein structure guides surface diffusion pathways for electron transport in membrane supercomplexes

Chun Kit Chan, Jonathan T. Nguyen, Corey F. Hryc, Chitrak Gupta, Matthew J. Guberman‐Pfeffer, Kevin Redding, William Dowhan, Matthew L. Baker, Alberto Pérez, Eugenia Mileykovskaya, Abhishek Singharoy

This study uses multiscale modeling and cryo-EM to show that transient protein structures guide electron transfer in mitochondrial supercomplexes, improving energy conversion efficiency by 30%.

Nature Communications · Feb 5, 2026Peer-reviewedBiophysics