Liver regeneration by oval cells employing bistability of stemness-senescence, Hippo signaling, EMT-MET, and polyploidy circuit
Marija Lazovska, Kristīne Salmiņa, Dace Pjanova, Pawel Zayakin, Bogdan I. Gerashchenko, Jekaterina Ērenpreisa
This paper investigates liver regeneration by oval cells, revealing a bistable switch between stemness and senescence regulated by Hippo signaling, EMT-MET, and polyploidy circuits.
npj Systems Biology and Applications · Apr 25, 2026Peer-reviewedCell Biology