Cell Biologynpj Systems Biology and ApplicationsPeer-reviewed
Liver regeneration by oval cells employing bistability of stemness-senescence, Hippo signaling, EMT-MET, and polyploidy circuit
Marija Lazovska, Kristīne Salmiņa, Dace Pjanova…·Jekaterina Ērenpreisa
This paper investigates liver regeneration by oval cells, revealing a bistable switch between stemness and senescence regulated by Hippo signaling, EMT-MET, and polyploidy circuits.
DOI 10.1038/s41540-026-00724-0