Deborah M. Hinton

A highly conserved sRNA downregulates multiple genes, including a sigma54 transcriptional activator, in the virulence mode of Bordetella pertussis

This paper identifies an sRNA, S17S, that downregulates multiple genes, including a sigma54 transcriptional activator, in the virulence mode of B. pertussis through complementary base pairing with ribosome binding sites.

The E. coli pathobiont LF82 encodes a unique variant of σ70 that results in specific gene expression changes and altered phenotypes

The paper identifies a single amino acid change in σ70 of LF82 E. coli that causes specific gene expression and phenotypic changes linked to its pathogenicity.