Author

Karolína Škopová

Czech Academy of SciencesORCID 0009-0004-1645-9286Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Abdul Samad· 1 shared Chin‐Hsien TaiiD· 1 shared Christopher S. HayesiD· 1 shared David Dongkyung KimiD· 1 shared David JurnečkaiD· 1 shared Deborah M. HintoniD· 1 shared Dominik PinkasiD· 1 shared Hernán LorenziiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

Abdul Samad

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2 papers

Recent·Most cited

C-terminal domain of the filamentous hemagglutinin FhaB is crucial for interaction of Bordetella pertussis with ciliated epithelial cells

David Jurnečka, Josef Chmelik, Jana Holubová, Ondřej Staněk, Petra Kasparova, Abdul Samad, Jana Prošková, Karolína Škopová, Markéta Dalecká, Dominik Pinkas, Peter Šebo, Christopher S. Hayes, Ladislav Bumba

This study identifies the C-terminal domain of FhaB as essential for Bordetella pertussis adhesion to ciliated epithelial cells and colonization, suggesting it as a candidate for improved vaccines.

bioRxiv · May 27, 2026 · PreprintMicrobiology

A highly conserved sRNA downregulates multiple genes, including a sigma54 transcriptional activator, in the virulence mode of Bordetella pertussis

Minji Sim, Jeffers Nguyen, Karolína Škopová, Kyungyoon Yoo, Chin‐Hsien Tai, Leslie Knipling, Qing Chen, David Dongkyung Kim, Summer Nolan, Rawan A. Elaksher, Nadim Majdalani, Hernán Lorenzi, Scott Stibitz, Kyung Duk Moon, Deborah M. Hinton

This paper identifies an sRNA, S17S, that downregulates multiple genes, including a sigma54 transcriptional activator, in the virulence mode of B. pertussis through complementary base pairing with ribosome binding sites.

mBio · Jul 8, 2025Peer-reviewedMicrobiology