Author

Linda S Rubio

Louisiana State University Health Sciences Center ShreveportORCID 0000-0002-7260-6971Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 3 Assay:DNA methylation· 3 Approach:experimental assay· 3 Organism:yeast· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Assay:Hi-C· 2 Research Focus:spatial domain detection· 2

Frequent Co-Authors

David S. GrossiD· 3 shared Suman MohajaniD· 3 shared Gurranna MaleiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

3 top collaborators · 3 mutual co-author links

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3 shared papersMolecular Biology

David S. GrossORCID

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3 papers

Recent·Most cited

Mediator Tail Subunits Hierarchically Couple Transcriptional Condensates to Gene Activation and Genome Organization

Gurranna Male, Suman Mohajan, Linda S Rubio, David S. Gross

The paper identifies Mediator Tail subunits' roles in coordinating transcriptional condensates, genome organization, and gene activation during heat shock in yeast.

bioRxiv · Apr 22, 2026 · PreprintMolecular Biology

Nuclear basket proteins Nup2 and Mlp1 drive heat shock-induced 3D genome restructuring downstream of transcriptional activation

Suman Mohajan, Linda S Rubio, David S. Gross

This study shows that Nup2 and Mlp1 drive 3D genome restructuring of HSR genes after transcriptional activation during heat shock in budding yeast.

Journal of Biological Chemistry · Aug 6, 2025Peer-reviewedCell Biology

Heat Shock Factor 1 forms nuclear condensates and restructures the yeast genome before activating target genes

Linda S Rubio, Suman Mohajan, David S. Gross

This paper shows that Hsf1 forms condensates and restructures the yeast genome before activating HSR genes in response to ethanol stress, with different kinetics compared to thermal stress.

eLife · Oct 15, 2024Peer-reviewedGenetics