Author

Maryam Tayefeh Jafari

Karolinska InstitutetORCID 0000-0002-7261-2191Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Amir Ata SaeiiD· 2 shared Hassan GharibiiD· 2 shared Hezheng LyuiD· 2 shared Roman A. ZubareviD· 2 shared Bohdana SokolovaiD· 1 shared Brady NilssoniD· 1 shared Hans von Holst· 1 shared Massimiliano GaetaniiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 30 mutual co-author links

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2 shared papersBiochemistry

Amir Ata SaeiORCID

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2 papers

Recent·Most cited

Above-Filter Digestion Proteomics reveals drug targets and localizes ligand binding site

Bohdana Sokolova, Hassan Gharibi, Maryam Tayefeh Jafari, Hezheng Lyu, Silvia Lovera, Massimiliano Gaetani, Amir Ata Saei, Roman A. Zubarev

The paper introduces AFDIP, a chemical proteomics method that identifies drug target binding sites with high structural resolution using digestion rate analysis and MD simulations.

Journal of Proteome Research · Feb 7, 2026Peer-reviewedBiochemistry

Massive solubility changes of neuronal proteins upon simulated traumatic brain injury reveal the role of shockwave in irreversible damage

Amir Ata Saei, Hassan Gharibi, Hezheng Lyu, Brady Nilsson, Maryam Tayefeh Jafari, Hans von Holst, Roman A. Zubarev

This study simulates traumatic brain injury using a dummy head to generate g-force and shockwave, revealing proteome solubility changes and identifying shockwave as the main cause of irreversible cell damage.

Molecules · Sep 22, 2023Peer-reviewedNeuroscience