Author

Pamela J. Yeh

Santa Fe InstituteORCID 0000-0002-7264-9509Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Evolutionary Biology· 1 Microbiology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:E. coli· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Tina Manzhu Kang· 2 shared Van M. SavageiD· 2 shared Bjørn Østman· 1 shared Brandon ChaniD· 1 shared Carolyn Xue· 1 shared Colin T. KremeriD· 1 shared Cynthia WhiteiD· 1 shared Elif TekiniD· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersSystems Biology

Tina Manzhu Kang

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Unexpected levels of antibiotic resistance in marine bacterial communities not solely explained by urban river discharge

Brandon Chan, Carolyn Xue, Natalie Ann Lozano-Huntelman, Karina Jimenez, Jennifer Ayla Jay, Pamela J. Yeh, Colin T. Kremer

The paper investigates antibiotic resistance in marine and freshwater bacterial communities, finding higher resistance in marine environments linked to species diversity rather than urban pollution.

bioRxiv · Nov 15, 2024 · PreprintMicrobiology

Prevalence and patterns of higher-order interactions

Elif Tekin, Cynthia White, Tina Manzhu Kang, Nina P. Singh, Mauricio Cruz‐Loya, Robert D. Damoiseaux, Van M. Savage, Pamela J. Yeh

The paper studies higher-order interactions in antibiotic combinations on Escherichia coli and finds they increase in frequency with more drugs, showing net synergy and emergent antagonism.

npj Systems Biology and Applications · Jul 31, 2018Peer-reviewedSystems Biology

Transitions in interaction landscapes of multidrug combinations

Tina Manzhu Kang, Bjørn Østman, Mauricio Cruz-Loya, Natalie Ann Lozano, Robert Damoiseaux, Van M. Savage, Pamela J. Yeh

The paper introduces interaction landscapes to visualize drug combinations' effects, showing drug interactions transition smoothly from antagonism to synergy with dose changes.

bioRxiv · Jul 11, 2018 · PreprintEvolutionary Biology