Bhanu Prakash V. L. Telugu

Loss of PAX4 results in disrupted endocrine pancreas development and neonatal diabetes in pigs

This paper shows that losing PAX4 in pigs causes severe diabetes and pancreatic issues, providing a model for studying PAX4's role in diabetes.

Directed conversion of porcine extended pluripotent stem cells into trophoblast-like stem cells through modulation of conserved TGF-β and ERK signaling pathways

This paper identifies biochemical conditions to convert porcine extended pluripotent stem cells into trophoblast-like stem cells by inhibiting TGF-β and ERK signaling.

Characterization of A Bronchoscopically Induced Transgenic Lung Cancer Pig Model for Human Translatability

This paper characterizes a bronchoscopically induced transgenic lung cancer pig model, showing high translatability to human lung cancer with significant transcriptome overlap.

A porcine germ cell depletion model to investigate the role of germ cells in gonadal development.

This study uses a porcine model to show that germ cell depletion leads to defects in gonadal somatic cell development, highlighting germ cells' role in shaping gonadal structure.

Derivation and characterization of chimera-competent eXtra-Embryonic eNdoderm 1 (XEN) cells from pig blastocysts

The paper derives and characterizes XEN cells from pig embryos, showing their ability to contribute to chimerism and serve as nuclear donors for cloning.