Pharmacology & ToxicologybioRxivPreprint
Using Patient iPSC-derived Retinal Pigment Epithelial Cells to Evaluate Differential Susceptibility to MEK Inhibitor-Associated Retinopathy
Lola P. Lozano, Timothy M. Boyce, Andrew P. Groves…·Budd A. Tucker
The paper compares MEK inhibitor effects on iPSC-derived RPE cells from patients with and without MEKAR, finding differential gene expression and phagocytic activity.
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