Author

Lola P. Lozano

University of IowaORCID 0000-0002-0492-4759Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Pharmacology & Toxicology· 2 Cell Biology· 1 Developmental Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 5 Research Focus:differential expression· 3 Approach:experimental assay· 3 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1

Frequent Co-Authors

Budd A. TuckeriD· 5 shared Robert F. MullinsiD· 4 shared Allison T. Wright· 2 shared Andrew P. VoigtiD· 2 shared Bradley A. EricksoniD· 2 shared Edwin M. StoneiD· 2 shared Elaine M. BinkleyiD· 2 shared H. Culver BoldtiD· 2 shared

Activity by Year

2023-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

5 shared papersPharmacology & Toxicology

Budd A. TuckerORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Pharmacology & ToxicologyUrologyPeer-reviewedAug 1, 2026

Validation and testing of an in vitro model to study medical treatments for anterior urethral stricture disease: assessing the potential efficacy of phosphodiesterase-4 (PDE4) inhibition and testosterone

Lola P. Lozano, Michael J. Volk, Carly D. Miller…·Bradley A. Erickson

The paper validates an in vitro model of anterior urethral stricture disease and evaluates the efficacy of PDE4 inhibitors and testosterone compared to paclitaxel.

DOI 10.1016/j.urology.2026.07.042

humanexperimental assay

𝕏 PostBluesky

Cell BiologybioRxivPreprintJun 24, 2026

Single-cell quantitative trait loci analyses identify expression changes in macular degeneration risk genes

Andrew P. Voigt, Nathaniel K. Mullin, Kelly Mulfaul…·Robert F. Mullins

The paper identifies expression changes in AMD risk genes using single-cell eQTL analysis across AMD stages and tissues.

DOI 10.64898/2026.03.30.714946

humanscRNA-seq

𝕏 PostBluesky

Pharmacology & ToxicologybioRxivPreprintApr 14, 2026

Using Patient iPSC-derived Retinal Pigment Epithelial Cells to Evaluate Differential Susceptibility to MEK Inhibitor-Associated Retinopathy

Lola P. Lozano, Timothy M. Boyce, Andrew P. Groves…·Budd A. Tucker

The paper compares MEK inhibitor effects on iPSC-derived RPE cells from patients with and without MEKAR, finding differential gene expression and phagocytic activity.

1 citation

humanbulk RNA-seq

𝕏 PostBluesky

Molecular BiologybioRxivPreprintOct 3, 2025

Modeling MEK inhibitor-Associated Retinopathy in vitro using human induced pluripotent stem cell-derived retinal pigment epithelial cells

Lola P. Lozano, Madeleine K. Jennisch, Renato Jensen…·Budd A. Tucker

This study investigates the effects of MEK inhibitor selumetinib on hiPSC-derived RPE cells, finding increased internalization of rod outer segments and decreased aquaporin 1 expression, suggesting a mechanism for MEKAR.

2 citations

humanexperimental assay

𝕏 PostBluesky

Developmental BiologybioRxivPreprintJun 30, 2023

Loss of NR2E3 disrupts rod photoreceptor cell maturation causing a fate switch late in human retinal development.

Nathaniel K. Mullin, Laura R. Bohrer, Andrew P. Voigt…·Budd A. Tucker

This study uses human retinal organoids to show that loss of NR2E3 disrupts rod photoreceptor maturation, leading to a fate switch to cone-like cells.

4 citations

humanscRNA-seq

𝕏 PostBluesky