Author

William J. Muller

Wake Forest University Health SciencesORCID 0000-0002-7293-4166Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Cezar M. KhursigaraiD· 1 shared David W.L.iD· 1 shared Dongdong WangiD· 1 shared Grace Mencfeld· 1 shared Graham P. HollowayiD· 1 shared Gregory R. SteinbergiD· 1 shared Henver S. BrunettaiD· 1 shared Jim PetrikiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Cezar M. KhursigaraORCID

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1 paper

Recent·Most cited

HER2-driven mammary tumorigenesis enhances bioenergetics despite reductions in mitochondrial content

Sara M. Frangos, Henver S. Brunetta, Dongdong Wang, Maria Joy Therese Jabile, Leslie M Jeffries, Grace Mencfeld, David W.L., William J. Muller, Cezar M. Khursigara, Kelsey H. Fisher‐Wellman, Jim Petrik, Gregory R. Steinberg, Graham P. Holloway

This study shows that HER2-driven mammary tumors have reduced mitochondrial content but increased respiration, suggesting HER2 signaling enhances mitochondrial bioenergetics independently of mitochondrial content.

bioRxiv · Nov 3, 2024Cancer Biology