Genome-wide association study provides new insights into the genetic architecture and pathogenesis of heart failure
Sonia H Shah, Albert Henry, Carolina Roselli, Honghuang Lin, Garðar Sveinbjörnsson, Ghazaleh Fatemifar, Åsa K. Hedman, Jemma B. Wilk, Michael P. Morley, Mark D. Chaffin, Anna Helgadóttir, Niek Verweij, Abbas Dehghan, Peter Almgren, Charlotte Andersson, , David J. Stott
This study conducts a large GWAS on heart failure, identifying 12 genetic loci with associations to CAD, atrial fibrillation, and reduced left ventricular function, and provides causal evidence for several risk factors.
bioRxiv · Jul 10, 2019 · PreprintGenetics