Author

Lena Ilan

University of TorontoORCID 0000-0002-7300-4606Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Alexander F. PalazzoiD· 1 shared En‐Ching LuoiD· 1 shared Gene Wei-Ming YeoiD· 1 shared Hamed Shateri NajafabadiiD· 1 shared Ines RabanoiD· 1 shared Nevraj S. Kejiou· 1 shared Nishani RajakulendraniD· 1 shared Stefan AigneriD· 1 shared

Activity by Year

2019-2019 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperMolecular Biology

Alexander F. PalazzoORCID

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1 paper

Recent·Most cited

Pyruvate Kinase M Links Glucose Availability to Protein Synthesis

Nevraj S. Kejiou, Lena Ilan, Stefan Aigner, En‐Ching Luo, Ines Rabano, Nishani Rajakulendran, Hamed Shateri Najafabadi, Stéphane Angers, Gene Wei-Ming Yeo, Alexander F. Palazzo

The paper shows that PKM inhibits translation of 7% of the transcriptome under high glucose and pyruvate conditions by stalling ribosome elongation, linking glycolysis to protein synthesis and cell cycle regulation.

bioRxiv · Jul 25, 2019 · PreprintMolecular Biology