Can Luo

CNVeil resolves haplotype-specific copy number and uncovers subclonal architecture hidden from total copy number profiling in single-cell cancergenomes

CNVeil infers haplotype-specific copy number and subclonal architecture from single-cell cancer genomes, outperforming existing methods in accuracy and resolution.

A little longer, a lot better: simulation-guided exploration of extended-length single-end barcoded reads for structural variant detection

This study evaluates long single-end barcoded reads for structural variant detection, showing improved accuracy with longer read lengths compared to short-read and pangenome-based methods.

FocalSV: target region-based structural variant assembly and refinement using single-molecule long read sequencing data

FocalSV improves structural variant detection by combining assembly-based precision with targeted analysis efficiency using long-read sequencing data.

Benchmarking clustering, alignment, and integration methods for spatial transcriptomics

This paper benchmarks clustering, alignment, and integration methods for spatial transcriptomics using real and simulated datasets, providing recommendations and code for reproducibility.

CNVeil enables accurate and robust tumor subclone identification and copy number estimation from single-cell DNA sequencing data

CNVeil improves tumor subclone identification and copy number estimation in single-cell DNA sequencing by addressing noise and bias through novel computational methods.