Anne‐Marie W. Turner

RelB proximity proteomics and CRISPR screening define chromatin regulators of noncanonical NF-κB control of HIV latency and reactivation

This study identifies chromatin regulators of HIV latency and reactivation using RelB proximity proteomics and CRISPR screening, revealing key acetyltransferases involved in noncanonical NF-κB pathway activation.

BET Degraders Reveal BRD4 Disruption of 7SK and P-TEFb is Critical for Effective Reactivation of Latent HIV in CD4+ T-cells

This study shows that BRD4 degraders are less effective than BET inhibitors in reactivating latent HIV in CD4+ T-cells, highlighting the importance of BRD4's role in disrupting 7SK and P-TEFb.