Author
University of North Carolina at Chapel HillORCID 0000-0003-3559-7356Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Waqas Ahmed, Xiaoyi Li, Ciniso Sylvester Shabangu…·Guochun Jiang
This paper identifies the ENL-USP7 complex as a host factor that stabilizes BRD4 to maintain HIV-1 latency and shows that disrupting this complex reactivates latent HIV.
Carley N Gray, Manickam Ashokkumar, Derek H. Janssens…·Michael Emerman
This study identifies INTS12 knockout as a method to enhance HIV latency reversal by overcoming a transcriptional block, improving reactivation in CD4 T cells from HIV-positive individuals.
Anne‐Marie W. Turner, Frances M. Bashore, Shane D. Falcinelli…·David M. Margolis
This study shows that BRD4 degraders are less effective than BET inhibitors in reactivating latent HIV in CD4+ T-cells, highlighting the importance of BRD4's role in disrupting 7SK and P-TEFb.