Author

Laurent Tesson

InsermORCID 0000-0002-7317-8921Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:rat· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Axel You· 2 shared Claire UsaliD· 2 shared Ignacio AnegóniD· 2 shared Marie Massoda· 2 shared Matthieu GiraudiD· 2 shared Séverine MénoretiD· 2 shared Séverine RemyiD· 2 shared Amada TorresiD· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersImmunology

Axel You

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintOct 8, 2026

A PATHOGENIC NFKB2 VARIANT CAUSES COMBINED IMMUNODEFICIENCY WITH THYMIC AND PERIPHERAL LYMPHOID DEFECTS IN RATS

Séverine Remy, Laurent Tesson, Claire Usal…·Ignacio Anegón

This study characterizes a rat model with a NFKB2 mutation, revealing systemic immunodeficiency with thymic and peripheral lymphoid defects.

DOI 10.64898/2026.10.02.756202

ratexperimental assay

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ImmunologybioRxivPreprintJun 19, 2026

Cross-species chromatin accessibility pinpoints HIVEP3 as a driver of thymic epithelial maturation and self-antigen expression, preventing chronic inflammation

Sümeyye Yayilkan, Marie Massoda, Séverine Ménoret…·Matthieu Giraud

This study identifies HIVEP3 as a critical regulator of thymic epithelial maturation and self-antigen expression, with its deficiency causing chronic inflammation.

DOI 10.64898/2026.06.16.732438

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GeneticsbioRxivPreprintJun 20, 2022

Epigenetic alterations in gut and brain of adult rats after oral administration of miR-320-3p and miR-375-3p at mid-lactation, and preventive potential of miR-320-3p on early weaning stress.

Gabriel Araújo Tavares, Amada Torres, Gwenola Le Dréan…·Bertrand Kaeffer

This study examines the effects of oral miR-320-3p and miR-375-3p delivery on gut and brain development in rats, showing miR-320-3p's potential to mitigate early weaning stress.

DOI 10.1101/2022.06.20.496755

ratbulk RNA-seq

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