Delyth Graham

This study identifies osteopontin as a mediator of impaired uterine artery remodelling in hypertensive pregnancy, showing its deficiency improves vascular function and fetal growth.

The paper identifies osteopontin (Spp1) as a positional and functional candidate gene for cardiac hypertrophy in SHRSP rats through congenic strain analysis and transcriptome profiling.

The paper investigates dominance and additivity in mammalian genetics, finding dominance accounts for 25% of heritable variance and reveals novel dominance QTLs and trans-acting effects in gene expression.