Author
University of GlasgowORCID 0000-0003-4913-3608Unclaimed ORCID profile · follow to get notified of new preprints
7 papers
Recent·Most cited
Cara Trivett, Tamara P. Martin, Amrita Asirvatham…·Martin McBride
The paper identifies osteopontin (Spp1) as a positional and functional candidate gene for cardiac hypertrophy in SHRSP rats through congenic strain analysis and transcriptome profiling.
Leilei Cui, Bin Yang, Shijun Xiao…·Lusheng Huang
The paper investigates dominance and additivity in mammalian genetics, finding dominance accounts for 25% of heritable variance and reveals novel dominance QTLs and trans-acting effects in gene expression.
Ιωάννα Ντάλλα, Lu-Chen C Weng, James Cartwright…·Dan M. Roden
This study identifies 210 genetic loci associated with the PR interval through multi-ancestry GWAS, highlighting their role in cardiac conduction and cardiovascular disease.
Alexander Teumer, Teresa Trenkwalder, Thorsten Kessler…·Wibke Reinhard
This study identifies a genome-wide significant association between a variant in the KCND3 gene and early repolarization pattern on ECG, suggesting a genetic basis for this trait.
Simon J. Haworth, Chin Yang Shapland, Caroline Hayward…·David K. Jackson
The paper identifies 9 novel genetic loci, including low-frequency variants in TP53, associated with head circumference and intracranial volume in up to 46,000 individuals.
Jianan Zhana, CHARGE ECG Working Group, Jessica van Setten…·Steven Ron Cummings
This paper introduces SAPPHO methods to detect pleiotropy in GWAS by modeling shared patterns of genetic associations, finding 16 additional and 124 novel loci in meta-analysis.
Jessica van Setten, Jennifer A. Brody, Yalda Jamshidi…·Paolo Gasparini
This study identifies 47 novel genetic loci associated with PR interval through genome-wide association meta-analysis across multiple populations.