Author

Cara Trivett

British Heart FoundationORCID 0000-0002-8136-6439Unclaimed ORCID profile · follow to get notified of new preprints

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Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Organism:rat· 1

Frequent Co-Authors

Christopher M. LoughreyiD· 2 shared Martin McBrideiD· 2 shared Aiste Monkeviciute· 1 shared Alexander S Johnston· 1 shared Ali Ali Mohamed ElbassioniiD· 1 shared Amrita Asirvatham· 1 shared Anmar RaheemiD· 1 shared Anna F. DominiczakiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersGenetics

Christopher M. LoughreyORCID

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2 papers

Recent·Most cited

Identification of osteopontin as a positional and functional candidate gene for cardiac hypertrophy in the SHRSP rat

Cara Trivett, Tamara P. Martin, Amrita Asirvatham, Kirsty Foote, Aiste Monkeviciute, Wendy Beattie, Christopher M. Loughrey, John McClure, Anna F. Dominiczak, Delyth Graham, Martin McBride

The paper identifies osteopontin (Spp1) as a positional and functional candidate gene for cardiac hypertrophy in SHRSP rats through congenic strain analysis and transcriptome profiling.

bioRxiv · Aug 27, 2026 · PreprintGenetics

Targeting Runx1 protects against heart failure with preserved ejection fraction

Ali Ali Mohamed Elbassioni, Anmar Raheem, Jian Hua Song, Alexander S Johnston, Cara Trivett, Hong Lin, Haobo Zhang, Ashley Bradley, Erin Higgins, Leanne Mooney, Yen Chin Koay, Dylan O’Toole, Pawel Herzyk, Colin Nixon, Karen Blyth, , Eilidh A. MacDonald

This study shows that inhibiting Runx1 protects against heart failure with preserved ejection fraction in mice by improving diastolic function and reducing hypertrophy and pulmonary edema.

bioRxiv · Jan 24, 2025 · PreprintPhysiology