Author

Zihan Dong

Yale UniversityORCID 0000-0002-7330-7981Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Research Focus:GWAS / association mapping· 2 Assay:GWAS summary statistics· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:polygenic risk· 1

Frequent Co-Authors

Hongyu ZhaoiD· 2 shared Andrew Thomas DeWaniD· 1 shared Biqing ZhuiD· 1 shared Chen LiniD· 1 shared Daiwei TangiD· 1 shared Hongyu LiiD· 1 shared Louise V. WainiD· 1 shared Maor SauleriD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersGenetics

Hongyu ZhaoORCID

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2 papers

Recent·Most cited

LDER-GE estimates phenotypic variance component of gene-environment interactions in human complex traits accurately with GE interaction summary statistics and full LD information

Zihan Dong, Wei Jiang, Hongyu Li, Andrew Thomas DeWan, Hongyu Zhao

Briefings in Bioinformatics · May 23, 2024Peer-reviewedGenetics

A Statistical Framework to Identify Cell Types Whose Genetically Regulated Proportions are Associated with Complex Diseases

Wei Liu, Wenxuan Deng, Ming Chen, Zihan Dong, Biqing Zhu, Zhaolong Yu, Daiwei Tang, Maor Sauler, Chen Lin, Louise V. Wain, Michael H. Cho, Naftali Kaminski, Hongyu Zhao

This paper introduces a statistical framework, cWAS, to identify cell types with genetically regulated proportions associated with complex diseases using integrated genetic and transcriptomics data.

PLoS Genetics · Jul 31, 2023Peer-reviewedGenetic & Genomic Medicine