Antje Prasse

This paper presents the first single-nucleus RNA sequencing atlas of pleuroparenchymal fibroelastosis, identifying novel cell states and their spatial organization in lung fibrosis.

This study shows clonal hematopoiesis promotes fibrosis by altering macrophage behavior and tissue repair processes in lung disease.

This study uses spatial transcriptomics to identify hybrid pro-inflammatory and pro-fibrotic cellular niches in sarcoidosis granulomas, linking them to fibrosis and immune responses.

This study develops a multi-omics framework to identify biomarkers of inhaled drug-induced lung toxicity using spatial transcriptomics, proteomics, and histopathological data.

The paper compares ectopic alveolar basal cells with airway basal cells in ILD patients, finding transcriptomic and organoid-forming differences but no evidence of AT2 cell origin.

The paper identifies genetic variants associated with chronic sarcoidosis phenotypes using genome-wide association studies and functional analysis.

This paper applies deconvolution to bulk RNA-seq data from idiopathic pulmonary fibrosis to identify cell-type specific pathway changes.

This study uses single-cell RNA sequencing to identify common and distinct immune aberrations in IPF and FHP, revealing shared monocyte features and disease-specific lymphocyte and receptor repertoires.