Hyun‐Dong Chang

Circulating extracellular vesicles display immunotherapeutic targets and complement circulating tumor DNA in high-risk neuroblastoma

The paper identifies tumor-associated surface markers on circulating extracellular vesicles as complementary biomarkers to circulating tumor DNA in high-risk neuroblastoma.

Giant bacteria in gut microbiomes

This study identifies Epulopiscium spp. in diverse hosts, including humans, and shows their abundance varies with age and disease states.

Heterogeneous signaling pathways are critical for the persistence of memory T cells in spleen and bone marrow

This study identifies tissue-specific signaling pathways critical for memory T cell persistence in spleen and bone marrow.

Mathematical modeling reveals a complex network of signaling and apoptosis pathways in the survival of memory plasma cells

The paper develops a mathematical model of plasma cell survival that integrates signaling and apoptosis pathways, revealing the essential roles of APRIL and stromal cell contact.