Author

Pawel Durek

German Rheumatism Research CentreORCID 0000-0002-6179-0670Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 3 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:flow cytometry· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Frederik HeinrichiD· 4 shared Mir‐Farzin MashreghiiD· 4 shared Abdolreza Nazari· 1 shared Ali MobasheriiD· 1 shared Anamika Giri· 1 shared Andrea Sánchez PeñaiD· 1 shared Andreas RadbruchiD· 1 shared Andy Roemhild· 1 shared

Activity by Year

2021-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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4 shared papersImmunology

Frederik HeinrichORCID

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4 papers

Recent·Most cited

ImmunologybioRxivPreprintSep 8, 2026

TLR-mediated activation of synovial fibroblasts from osteoarthritis patients promotes chondrocyte dysfunction

Yujie Dai, Ao Gong, Nayar Durán-Hernández…·Ping Shen

This study shows that TLR activation in OA synovial fibroblasts leads to inflammatory responses and chondrocyte dysfunction.

DOI 10.64898/2026.09.04.749398

humanbulk RNA-seq

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ImmunologyMolecular Therapy AdvancesPeer-reviewedApr 9, 2026

Clinical development of gene edited tacrolimus-resistant Treg (FKBP12KO-Treg) to enable simultaneous immunosuppression and support of immune regulation

Ghazaleh Zarrinrad, Lisa-Marie Burkhardt, C. Beltran-Mestres…·Leila Amini

This paper develops gene-edited tacrolimus-resistant Treg cells (FKBP12KO-Treg) for clinical use in transplant recipients, showing they maintain immunoregulatory function while resisting tacrolimus.

2 citationstop 5%

humanflow cytometry

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ImmunologybioRxivPreprintApr 6, 2026

Heterogeneous signaling pathways are critical for the persistence of memory T cells in spleen and bone marrow

Emilia Schneider Revueltas, Lukas Almes, Koji Tokoyoda…·Andreas Radbruch

This study identifies tissue-specific signaling pathways critical for memory T cell persistence in spleen and bone marrow.

1 citation

mouseflow cytometry

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Molecular BiologyOsteoarthritis and CartilagePeer-reviewedMar 21, 2021

Combining segmental bulk- and single-cell RNA-sequencing to define the chondrocyte gene expression signature in the murine knee joint

Vikram Sunkara, Gitta Anne Heinz, Frederik Heinrich…·Annemarie Lang

This study combines bulk and single-cell RNA-seq to identify chondrocyte gene expression in murine knee joints, finding 75 overlapping genes related to cartilage homeostasis and osteoarthritis.

22 citations

mousebulk RNA-seq

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