Author

Mark B. Hampton

University of OtagoORCID 0000-0002-7349-3729Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Aaron J. StevensiD· 1 shared Andrew B. DasiD· 1 shared Annika R. SeddoniD· 1 shared Ashleigh S. JohnsiD· 1 shared Borries DemeleriD· 1 shared Christopher R Horne· 1 shared David M. WoodiD· 1 shared Heather L. SheareriD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMolecular Biology

Aaron J. StevensORCID

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2 papers

Recent·Most cited

Mechanism of NanR transcriptional activation of sialic acid metabolism in Streptococcus pneumoniae.

David M. Wood, Ashleigh S. Johns, Zachary D. Tillett, Heather L. Shearer, Santosh Panjikar, Yee-Foong Mok, Michael D. W. Griffin, Timothy M. Allison, Rachel A. North, Paul Pace, Borries Demeler, Mark B. Hampton, Renwick C. J. Dobson, Christopher R Horne

This study identifies how SpNanR activates sialic acid metabolism in S. pneumoniae by binding N-acetylmannosamine-6-phosphate, stabilizing its tetramer and enhancing transcription of the nan and siaA operons.

Nucleic Acids Research · Sep 22, 2026Peer-reviewedMolecular Biology

Site-specific decreases in DNA methylation in replicating cells following exposure to oxidative stress

Annika R. Seddon, Andrew B. Das, Mark B. Hampton, Aaron J. Stevens

The paper shows that oxidative stress from chloramine exposure causes site-specific DNA methylation decreases in Jurkat T-lymphoma cells, affecting transcription and potentially contributing to epigenetic instability.

Human Molecular Genetics · Sep 13, 2022Peer-reviewedMolecular Biology