Takashi Okada

Uncovering Bifurcation Behaviors of Biochemical Reaction Systems from Network Topology

This paper introduces Structural Bifurcation Analysis (SBA) to identify bifurcation behaviors in biochemical networks from topology, applied to macrophage polarization revealing structural constraints and gene-dependent patterns.

Origin of diverse phosphorylation patterns in the ERBB system

The paper investigates how differences in ERBB receptor expression and phosphorylation rates contribute to diverse phosphorylation dynamics across organs.