Molecular BiologyBMC Molecular and Cell BiologyPeer-reviewed
Mechanism of hERG inhibition by gating-modifier toxin, APETx1, deduced by functional characterization
Kazuki Matsumura, Takushi Shimomura, Yoshihiro Kubo…·Masanori Osawa
This study identifies key residues in APETx1 and hERG that mediate inhibition by stabilizing the resting state of the hERG channel.
13 citations