Masahiro Fukuda

The paper develops a geometric model to explain how the nucleus limits phagocytosis by deriving quantitative relationships between target geometry and nuclear exclusion.

This paper introduces a pipeline combining AI-assisted construct screening and de novo protein design to rapidly determine high-resolution GPCR structures, validated on multiple receptors.

This study presents cryo-EM structures of ChR024, revealing its color-tuning mechanism and transition from a proton pump to a light-gated channel.

The paper uses a machine-learning model to predict red-shifted channelrhodopsin variants, identifying ChR024 with a maximum absorption wavelength of ~578 nm for optogenetics.

This study identifies key residues in APETx1 and hERG that mediate inhibition by stabilizing the resting state of the hERG channel.