A Novel Multiplex qPCR Assay for Detection of Plasmodium falciparum with Histidine-rich Protein 2 and 3 (pfhrp2 and pfhrp3) Deletions in Polyclonal Infections
Lynn Grignard, Debbie Nolder, Nuno Sepúlveda, Araia Berhane, Selam Mihreteab, Robert Diotrephes Kaaya, Jody Emile Phelan, Kara A. Moser, Donelly A. van Schalkwyk, Susana G. Campino, Jonathan B. Parr, Jonathan J. Juliano, Peter L. Chiodini, Jane A. Cunningham, Colin J. Sutherland, , Khalid B. Beshir
This paper develops a multiplex qPCR assay to detect Plasmodium falciparum and identify pfhrp2 and pfhrp3 deletions in field samples with high sensitivity and specificity.
EBioMedicine · May 1, 2020Peer-reviewedGenetics