Jonathan B. Parr

This study profiles bacterial communities in genital and non-genital skin ulcers from Ghana, finding similar diversity but distinct compositions, with genital lesions enriched in Gardnerella and non-genital lesions in Staphylococcus and others.

The paper functionally validates the Plasmodium falciparum K13 C580Y mutation in Ethiopian isolates, showing it confers artemisinin tolerance.

This study characterizes malaria vector dynamics in Kinshasa Province over four years, identifying An. gambiae s.l. as the dominant species and highlighting emerging roles for An. paludis in rural areas, alongside widespread insecticide resistance.

This study analyzes Treponema pallidum strains in Buenos Aires, Argentina, using whole genome sequencing and tprK locus analysis to understand transmission dynamics and lineage-specific diversity.

The paper analyzes the spread of Plasmodium falciparum with hrp2/3 deletions in Peru, finding that demographic changes from malaria control and potential selection pressures drove their fixation.

The paper analyzes sequence variability of BamA and FadL outer membrane proteins in 186 Treponema pallidum strains to identify evolutionary patterns and vaccine targets.

The paper develops MAD4HatTeR, an amplicon sequencing panel and analysis pipeline for detecting Plasmodium falciparum diversity, resistance markers, and gene duplications/deletions, showing high sensitivity and reproducibility across settings.

The paper investigates the virome of Aedes mosquitoes near the DRC-Angola border, finding evidence of dengue virus transmission and a diverse virome including other viruses.

The paper develops a fluorescent Treponema pallidum strain to study spirochete-host interactions and antibody-mediated clearance, showing greater OM disruption with sera from rabbits infected with the Nichols strain.

The paper analyzes whole-genome-sequenced Plasmodium falciparum samples to understand gene deletions associated with malaria rapid diagnostic tests, identifying patterns of chromosomal rearrangements and duplication.

This study performs population genomic analysis of Plasmodium ovale species in sub-Saharan Africa, finding differences in nucleotide diversity and signatures of selection between the two species.

Novel malaria SHERLOCK assays enabled robust detection, speciation, and genotyping of Plasmodium spp. in diverse samples collected in Africa and Asia.

The paper sequences Treponema pallidum from Chinese syphilis chancres using improved whole-genome sequencing methods without rabbit passage, revealing genetic diversity in China.

This paper develops a multiplex qPCR assay to detect Plasmodium falciparum and identify pfhrp2 and pfhrp3 deletions in field samples with high sensitivity and specificity.

This study analyzes the genetic structure of Plasmodium falciparum in the DRC, identifying an east-west haplotype divide linked to antimalarial resistance and evidence of gene flow and selection pressures.

The paper uses whole-genome sequencing to show that Plasmodium falciparum parasites in Zanzibar and mainland Tanzania share genetic ancestry, indicating ongoing importation despite malaria control efforts.