Jonathan J. Juliano

Functional validation of the Plasmodium falciparum K13 C580Y mutation in recently collected Ethiopian isolates

The paper functionally validates the Plasmodium falciparum K13 C580Y mutation in Ethiopian isolates, showing it confers artemisinin tolerance.

Malaria entomological surveillance in Kinshasa Province: A longitudinal study

This study characterizes malaria vector dynamics in Kinshasa Province over four years, identifying An. gambiae s.l. as the dominant species and highlighting emerging roles for An. paludis in rural areas, alongside widespread insecticide resistance.

Malaria control and the unexpected spread of diagnostic-resistant Plasmodium falciparum in Peru

The paper analyzes the spread of Plasmodium falciparum with hrp2/3 deletions in Peru, finding that demographic changes from malaria control and potential selection pressures drove their fixation.

A novel locus associated with decreased susceptibility of Plasmodium falciparum to lumefantrine and dihydroartemisinin has emerged and spread in Uganda

Highly multiplex molecular inversion probe panel in Plasmodium falciparum targeting common SNPs approximates whole genome sequencing assessments for selection and relatedness

The paper develops a targeted sequencing panel for Plasmodium falciparum that approximates whole genome sequencing for population genetics analyses.

Evidence of dengue virus transmission and a diverse Aedes mosquito virome on the Democratic Republic of Congo-Angola border

The paper investigates the virome of Aedes mosquitoes near the DRC-Angola border, finding evidence of dengue virus transmission and a diverse virome including other viruses.

Interchromosomal segmental duplication drives translocation and loss of P. falciparum histidine-rich protein 3

The paper analyzes whole-genome-sequenced Plasmodium falciparum samples to understand gene deletions associated with malaria rapid diagnostic tests, identifying patterns of chromosomal rearrangements and duplication.

Population genomics of Plasmodium ovale species in sub-Saharan Africa

This study performs population genomic analysis of Plasmodium ovale species in sub-Saharan Africa, finding differences in nucleotide diversity and signatures of selection between the two species.

Genetic polymorphism and evidence of signatures of selection in the Plasmodium falciparum circumsporozoite protein gene in Tanzanian regions with different malaria endemicity

This study analyzes genetic diversity and selection signatures in the Pfcsp gene of Plasmodium falciparum from Tanzanian regions with varying malaria transmission to inform vaccine development.

Examining the early distribution of the artemisinin-resistant Plasmodium falciparum kelch13 R561H mutation in Rwanda

The paper examines the early distribution of the Pfk13-R561H mutation in Rwanda using blood spot samples from a demographic health survey, finding spatial clustering of the mutation.

Genomic Epidemiology of Escherichia coli Isolates from a Tertiary Referral Center in Lilongwe, Malawi

This study uses whole genome sequencing to analyze the prevalence and spread of antimicrobial resistance genes in E. coli isolates from Malawi, showing increased prevalence of ST131 and blaCTX-M-15.

Describing the current status of Plasmodium falciparum population structure and drug resistance within mainland Tanzania using molecular inversion probes

The paper analyzes genetic diversity and drug resistance mutations in Tanzanian Plasmodium falciparum isolates using molecular inversion probes, revealing population structure and geographic patterns of genetic relatedness.

Analysis of Treponema pallidum strains from China using improved methods for whole-genome sequencing from primary syphilis chancres

The paper sequences Treponema pallidum from Chinese syphilis chancres using improved whole-genome sequencing methods without rabbit passage, revealing genetic diversity in China.

A Novel Multiplex qPCR Assay for Detection of Plasmodium falciparum with Histidine-rich Protein 2 and 3 (pfhrp2 and pfhrp3) Deletions in Polyclonal Infections

This paper develops a multiplex qPCR assay to detect Plasmodium falciparum and identify pfhrp2 and pfhrp3 deletions in field samples with high sensitivity and specificity.

The Impact of Antimalarial Resistance on the Genetic Structure of Plasmodium falciparum in the DRC

This study analyzes the genetic structure of Plasmodium falciparum in the DRC, identifying an east-west haplotype divide linked to antimalarial resistance and evidence of gene flow and selection pressures.

Falciparum malaria from coastal Tanzania and Zanzibar remains highly connected despite effective control efforts on the archipelago

The paper uses whole-genome sequencing to show that Plasmodium falciparum parasites in Zanzibar and mainland Tanzania share genetic ancestry, indicating ongoing importation despite malaria control efforts.