FGF2 and BMP4 influence on FGFR2 dynamics during the segregation of epiblast and primitive endoderm cells in the pre-implantation mouse embryo
Marcelo Demarchi Goissis, Brian Bradshaw, Eszter Pósfai, Janet Rossant
This study examines FGFR2 dynamics in mouse embryos, showing its correlation with PE cells increases during blastocyst development, supporting FGF's role in maintaining rather than initiating the PE lineage.
bioRxiv · Dec 9, 2022 · PreprintDevelopmental Biology