Loss of presenilin-1 in smooth muscle cells ameliorates elastin aortopathy
Junichi Saito, Jui M. Dave, Freddy Duarte Lau, Daniel M. Greif
This study shows that deleting Psen1 in smooth muscle cells reduces Notch activity and improves elastin aortopathy in mice.
bioRxiv · Apr 15, 2023 · PreprintDevelopmental Biology