Author

Junichi Saito

Yale UniversityORCID 0000-0002-4297-727XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:protein structure· 1

Frequent Co-Authors

Daniel M. GreifiD· 2 shared Jui M. DaveiD· 2 shared Eunate Gallardo‐VaraiD· 1 shared Freddy Duarte LauiD· 1 shared George TellidesiD· 1 shared Inamul KabiriD· 1 shared Nandhini Sadagopan· 1 shared Robert Kirk RiemeriD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersDevelopmental Biology

Daniel M. GreifORCID

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2 papers

Recent·Most cited

Developmental BiologyNature Cardiovascular ResearchPeer-reviewedJan 5, 2026

Sphingosine kinase 1 is integral for elastin deficiency-induced arterial hypermuscularization

Junichi Saito, Jui M. Dave, Eunate Gallardo‐Vara…·Daniel M. Greif

This study identifies SPHK1 as a key driver of SMC hyperproliferation in elastin deficiency, showing its role in both pathological and physiological arterial remodeling.

2 citations

mousehuman

Developmental BiologybioRxivPreprintApr 15, 2023

Loss of presenilin-1 in smooth muscle cells ameliorates elastin aortopathy

Junichi Saito, Jui M. Dave, Freddy Duarte Lau, Daniel M. Greif

This study shows that deleting Psen1 in smooth muscle cells reduces Notch activity and improves elastin aortopathy in mice.

DOI 10.1101/2023.04.15.536809

mouseexperimental assay