Rodrigo Ibarra‐García‐Padilla

This study shows that MYCN overexpression in zebrafish sympathoadrenal progenitors leads to an expanded NCC gene signature and disrupted BMP signaling, contributing to neuroblastoma-like developmental changes.

The paper uses in toto imaging and single-cell tracing in zebrafish to show that Ret signaling regulates ENCC proliferation and migration, leading to HSCR-like phenotypes.

The paper creates a single-cell atlas of neural crest cell derivatives in zebrafish, identifying multiple cell types and subtypes and their gene expression patterns.