Phosphorylation of VapB antitoxins affects intermolecular interactions to regulate VapC toxin activity in Mycobacterium tuberculosis
Basanti Malakar, Valdir C. Barth, Júlia Puffal, Nancy A. Woychik, Robert N. Husson
This study shows that phosphorylation of VapB antitoxins in M. tuberculosis alters their interactions with VapC toxins and promoter DNA, thereby regulating toxin activity and bacterial survival.
Journal of Bacteriology · Sep 24, 2024Peer-reviewedMicrobiology