The neurodevelopmental disorder-linked PHF14 complex that forms biomolecular condensates detects DNA damage and promotes repair
Eva-Lotta Käsper, In-Young Hwang, Helga Grötsch, Herman K.H. Fung, Aurélien A. Sérandour, Niccolò Arecco, Ronald Oellers, Patryk Poliński, Almudena Garcia Gomez-Monedero, Christoph W. Müller, Kyung‐Min Noh
This study identifies the PHF14 complex's role in DNA damage detection and repair through biomolecular condensate formation, showing its importance in neural progenitor cell function.
bioRxiv · Oct 12, 2021 · PreprintMolecular Biology