Author

Silvie Franck

Vrije Universiteit BrusselORCID 0000-0002-7433-8587Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Assay:DNA methylation· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Alexander GheldofiD· 1 shared Claudia SpitsiD· 1 shared Dominika DziedzickaiD· 1 shared Fien VanroyeiD· 1 shared Geoffrey Duqué· 1 shared Joke Allemeersch· 1 shared Joris Robert VermeeschiD· 1 shared Karen SermoniD· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenetics

Alexander GheldofORCID

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1 paper

Recent·Most cited

MSH2 knock-down shows CTG repeat stability and concomitant upstream demethylation at the DMPK locus in myotonic dystrophy type 1 human embryonic stem cells

Silvie Franck, Lise Barbé, Simon Ardui, Yannick De Vlaeminck, Joke Allemeersch, Dominika Dziedzicka, Claudia Spits, Fien Vanroye, Pierre Hilven, Geoffrey Duqué, Joris Robert Vermeesch, Alexander Gheldof, Karen Sermon

This study shows that MSH2 knock-down stabilizes CTG repeats and reduces upstream CpG methylation in DM1 hESCs, suggesting a link between DNA repair and epigenetic changes in DM1.

Human Molecular Genetics · Nov 1, 2020Peer-reviewedGenetics