Author

Dominika Dziedzicka

Vrije Universiteit BrusselORCID 0000-0002-5277-9728Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1 Approach:statistical model· 1

Frequent Co-Authors

Carola Maria MorelliD· 2 shared Ludovic VallieriD· 2 shared Alexander GheldofiD· 1 shared Alice VickersiD· 1 shared Andrew Christopher HodgsoniD· 1 shared Annabelle WurmseriD· 1 shared Blaise LouisiD· 1 shared Brandon Tyler WesleyiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersDevelopmental Biology

Carola Maria MorellORCID

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Author profile →

4 papers

Recent·Most cited

Mechanical signalling through collagen I regulates cholangiocyte specification and tubulogenesis during liver development

Iona G. Thelwall, Carola Maria Morell, Dominika Dziedzicka, Lucia Cabriales, Andrew Christopher Hodgson, Floris J.M. Roos, Louis M. Elfari, Ludovic Vallier, Kevin J. Chalut

This study shows that collagen I mechanical signaling in synthetic hydrogels promotes cholangiocyte differentiation and bile duct formation from hiPSCs.

Development · Oct 29, 2026Peer-reviewedDevelopmental Biology

Generation of functional hepatocytes by forward programming with nuclear receptors

Rute A. Tomaz, Ekaterini D. Zacharis, Fabian Bachinger, Annabelle Wurmser, Daniel Yamamoto, Sandra Petrus-Reurer, Carola Maria Morell, Dominika Dziedzicka, Brandon Tyler Wesley, Imbisaat Geti, Charis‐Patricia Segeritz, Miguel Cardoso de Brito, Mariya Chhatriwala, Daniel Ortmann, Kourosh Saeb‐Parsy, Ludovic Vallier

This study generates functional hepatocytes from human pluripotent stem cells using forward programming with nuclear receptors, bypassing the limitations of traditional differentiation methods.

eLife · Jul 26, 2022Peer-reviewedDevelopmental Biology

MSH2 knock-down shows CTG repeat stability and concomitant upstream demethylation at the DMPK locus in myotonic dystrophy type 1 human embryonic stem cells

Silvie Franck, Lise Barbé, Simon Ardui, Yannick De Vlaeminck, Joke Allemeersch, Dominika Dziedzicka, Claudia Spits, Fien Vanroye, Pierre Hilven, Geoffrey Duqué, Joris Robert Vermeesch, Alexander Gheldof, Karen Sermon

This study shows that MSH2 knock-down stabilizes CTG repeats and reduces upstream CpG methylation in DM1 hESCs, suggesting a link between DNA repair and epigenetic changes in DM1.

Human Molecular Genetics · Nov 1, 2020Peer-reviewedGenetics

High-throughput micro-patterning platform reveals Nodal-dependent dissection of peri-gastrulation-associated versus pre-neurulation associated fate patterning

Mukul Tewary, Dominika Dziedzicka, Joel Östblom, Laura Prochazka, Nika Shakiba, Tiam Heydari, Daniel Aguilar‐Hidalgo, Curtis M. Woodford, Elia Piccinini, David Becerra‐Alonso, Alice Vickers, Blaise Louis, Nafees Rahman, Davide Danovi, Mieke Geens, , Peter W. Zandstra

The paper develops an in vitro platform to study fate patterning in hPSCs, revealing Nodal-dependent switches between gastrulation and neurulation-associated gene profiles.

PLoS Biology · Oct 21, 2019Peer-reviewedDevelopmental Biology