Jaclyn M Noshay

RWRtoolkit enables multi-omic network analysis using random walks on multiplex networks across any species, providing tools for topological analysis and statistical evaluation.

This paper develops a novel feature set and public resource for predicting CRISPR-Cas9 sgRNA efficiency using quantum chemical tensors and explainable-AI methods.

The paper uses DNA methylation profiles from a single tissue to identify unmethylated regions (UMRs) that mark expressed genes and cis-regulatory elements in plant genomes.

The paper identifies variable transposable element (TE) insertions across four maize genomes, showing their role in genome organization and gene content variation.

The paper describes a transgenerational epigenetic decline in vigor and viability in maize-teosinte backcross populations, termed 'hybrid decay', characterized by genomic instability and altered gene expression.